2018-11-08 13:01:172025-03-26 16:30:55
description
intramembrane metalloprotease, processing of pro-sigma-K to active [[protein|SigK]]
intramembrane metalloprotease (site 2 protease), processing of pro-sigma-K to active [[protein|SigK]]
locus
BSU27970
BSU_27970
geneLength
864
867
outlinks
bsu
BSU27970
BSU_27970
Gene
Coordinates
2,855,973 → 2,856,839
2,855,973 2,856,839
The protein
Protein family
peptidase M50B family (according to Swiss-Prot)
[SW|peptidase M50B family] (according to UniProt)
The protein
Effectors of protein activity
ATP regulates substrate access to the active site and renders cleavage sensitive to the cellular energy level [Pubmed|19805276]
[[protein|SpoIVFB]] is kept inactive by the interaction with [[protein|SpoIVFA]] and [[protein|BofA]]
ATP regulates substrate access to the active site and renders cleavage sensitive to the cellular energy level [Pubmed|19805276]
[[protein|SpoIVFB]] is kept inactive by the interaction with [[protein|SpoIVFA]] and [[protein|BofA]] [pubmed|15087499]
Biological materials
Mutant
BKE27970 (Δ[[gene|spoIVFB]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE27970 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GATCTTTAAGATAAGGTCGA, downstream forward: _UP4_TAAAACTGATTGACAAACGC
BKK27970 (Δ[[gene|spoIVFB]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK27970 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GATCTTTAAGATAAGGTCGA, downstream forward: _UP4_TAAAACTGATTGACAAACGC
BKE27970 ([[gene|spoIVFB]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE27970 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GATCTTTAAGATAAGGTCGA, downstream forward: _UP4_TAAAACTGATTGACAAACGC
BKK27970 ([[gene|spoIVFB]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK27970 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GATCTTTAAGATAAGGTCGA, downstream forward: _UP4_TAAAACTGATTGACAAACGC
References
Reviews
References
Original Publications
References
Original Publication